产品货号：
Z38836
中文名称：
VDR抗体
英文名称：
Anti-VDR Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-VDR Antibody |
| 指标别名 | VDR;NR1I1;Vitamin D3 receptor;VDR;1;25-dihydroxyvitamin D3 receptor;Nuclear receptor subfamily 1 group I member 1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | VDR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Vitamin D Receptor |
| 实际分子量 | 48KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | VDR(Vitamin D Receptor),also known as Vitamin D Hormone Receptor,is a member of the nuclear receptor family of transcription factors.Labuda et al.(1991) assigned the VDR gene to 12q12-q14 by in situ hybridization.Using mutation analysis,Jurutka et al.(2000) characterized arg18/arg22,VDR residues immediately N-terminal of the first DNA-binding zinc finger,as vital for contact with the general transcription factor IIB(TFIIB).A natural polymorphic variant of VDR,termed F/M4(missing a FokI restriction site),which lacks only the first 3 amino acids(including glu2),interacted more efficiently with TFIIB and also possessed elevated transcriptional activity compared with the full-length(f/M1) receptor.Shah et al.(2006) stated that the signaling and oncogenic activity of beta-catenin(CTNNB1) can be repressed by activation of VDR.Conversely,high levels of beta-catenin can potentiate the transcriptional activity of 1,25-dihydroxyvitamin D3. |
| Uniprot ID | P11473 |
| 基因名全称 | Vitamin D3 receptor |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：VDR抗体，VDR单抗，Anti-VDR Antibody